I have seen an advert for the StatinWISE trial and I'd like to find out more. What should I do next?
Welcome to the StatinWISE website! StatinWISE is a trial designed to find out whether statins cause muscle symptoms. If you have experienced muscle symptoms while using statins and want to find out whether statins are causing your symptoms, then StatinWISE could be for you!
Watch our videos and have a look through the website to find out more about the trial. If you think you might be interested in taking part, then click on 'Patient expression of interest form" and somebody from the trial team will get in touch with you.
I have been invited to take part in the StatinWISE trial. What should I do next?
We're really pleased that you're considering taking part. Your GP should have given you an information leaflet about the StatinWISE study. You can see an example leaflet by clicking this link. If you would like to take part or find out more, then contact your practice directly using the number on the back of your Patient Information Sheet. If you're unsure then contact us and we'll put you in touch with the right person.
What is required of me?
You will go to your GP surgery for a baseline visit, where a research nurse will explain the trial to you and make sure you are suitable.
Your study medication will be sent directly to you in the post. The packs have been designed to fit through your letterbox. You will be asked to take one pill every day for one year. Every two months, you will be asked to tell us about your muscle symptoms for seven days and to fill in one questionnaire. You can do this using our mobile app, website, over the telephone, or using pen and paper.
At the end of your trial (one year), there will be one phone call or face to face appointment so that you can see your results and discuss whether or not to continue using statins.
What's in it for me?
If you take part in StatinWISE, then you will be closely monitored for the duration of the trial and all of your relevant blood tests will be up to date.
The results of the trial will be personalised to you. You will find out whether your muscle symptoms are worse when you are taking statins compared to placebo. This will help you to decide whether to continue taking statins or not.
I am a patient with symptoms that I think are caused by statins. How can I join the trial?
You can take part in the StatinWISE trial if your general practice is one of our collaborators and you meet our eligibility criteria:
- You must have been previously prescribed statins;
- You must either have stopped taking your statins within the last 3 years or you are considering stopping them due to muscle-related side-effects;
- Your GP must believe that you are eligible for the trial;
- You must be over the age of 16.
We are currently seeking approval to open two recruitment centres in London. If you meet the eligibility criteria above, and can attend one of our centres, then you can join StatinWISE. Keep an eye on our website or express your interest to find out when our recruitment centres will open.
If your general practice is not in our list of collaborators and you are unable to attend one of our London recruitment centres, then you can't currently take part in StatinWISE. For more information, please contact us.
I have questions about my treatment. What should I do?
If you have any questions or concerns about your treatment, please contact your doctor in the first instance.
My next treatment pack hasn't arrived. What should I do?
If your next treatment pack hasn't arrived, then contact the CTU.
I'm having trouble submitting my symptom data.
Contact the CTU to let us know.
I forgot to take my study medication. What should I do?
Continue taking your doses as scheduled. At the end of the two-month treatment period, you will receive a questionnaire asking about your use of study medication. Make sure you fill this in to let us know that you have missed any days' pills. And don't forget to return any unused medication to us in the envelope provided with your treatment pack.